Monitoring and Optimization of Cerebral Perfusion Pressure in Post-cardiac Arrest Patients: a Pilot Study
National Taiwan University Hospital
50 participants
Dec 10, 2024
INTERVENTIONAL
Conditions
Summary
The goal of this study is to establish the ICP and CPP monitoring process and analyze the results in post-arrest patients, to validate the correlation between direct and non-invasive ICP monitoring indicators, to establish a protocol of management of elevated ICP and insufficient CPP in post-arrest care, to establish a protocol for personalizing CPP and MAP optimization, and to analyze its impact on neuroprognosis. Participants will receive ICP monitoring within 12 hours post-ROSC if meet all inclusion and exclusion criteria.
Eligibility
Inclusion Criteria4
- non-traumatic cardiac arrest
- admitted to ICU
- GCS: motor <=5
- severity: TIMECARD score medium-risk group
Exclusion Criteria9
- traumatic cardiac arrest
- pregnancy
- intracranial hemorrhage
- coagulopathy
- anti-platelet or anti-coagulation use
- terminal illness
- pre-arrest CPC score >=3
- GWR < 1.2 on CT or severe hypoxic ischemic encephalopathy
- CNS infection
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Interventions
ICP monitoring
Locations(1)
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NCT06601842