Prophylactic Tranexamic Acid To Reduce Blood Loss During Caesarean Delivery.
Prophylactic Role Of Tranexamic Acid To Reduce Blood Loss During Caesarean Delivery : A Prospective Study.
Aligarh Muslim University
300 participants
Oct 1, 2024
INTERVENTIONAL
Conditions
Summary
Postpartum hemorrhage continues to be the leading cause of maternal morbidity and mortality. Globally, it is responsible for 25% of all pregnancy-related deaths. PPH is unpredictable and may occur in the absence of risk factors. Tranexamic acid is an antifibrinolytic proven to reduce blood loss and transfusion requirements for various surgeries. This study aims to explore the effectiveness of tranexamic acid as an adjunct to other uterotonics before the Caesarian Section.
Eligibility
Inclusion Criteria2
- The women undergoing cesarean delivery (both elective and emergency) during the study period.
- Willing to participate in the study after understanding the concept.
Exclusion Criteria3
- Critically ill patient.
- Not willing to give consent to participate in the study
- Cases diagnosed with a ruptured uterus or undergoing caesarian hysterectomy during operation.
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Interventions
All women recruited to Group A will receive tranexamic acid 1 gram in 100 ml Normal Saline as intravenous infusion 10 minutes before the skin incision.
All women recruited to Group B will receive 100 ml Normal Saline as intravenous infusion 10 minutes before the skin incision.
Locations(1)
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NCT06604325