RecruitingNCT06604338

Genomics and Microbiome Investigation in Cases of Recurrent Pregnancy Losses

Evaluation of Predisposing Factors for Idiopathic Recurrent Pregnancy Losses: a Study Using a Genomic and Microbiota Approach

Sponsor

Hospital de Clinicas de Porto Alegre

Enrollment

20 participants

Start Date

Apr 14, 2023

Study Type

OBSERVATIONAL

Conditions

Recurrent Pregnancy Loss(RPL)

Summary

Recurrent pregnancy losses (RPL) are characterized by the occurrence of more than one spontaneous pregnancy loss. It is caused by different known factors, but about half of the cases remain without an explanation. Efforts are being done in the scientific community to solve this cases. In this study, the investigators aim to investigate genetic factors that might predispose to RPL, as well as the influence of the uterine microbiota (microorganisms that normally live in the uterus of women).

Eligibility

Sex: FEMALE

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Exome test and Microbiota analysis for people with recurrent pregnancy loss(rpl). The study is currently recruiting participants at 1 location. People eligible for this study include women.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTExome test

An exome will be performed on the participants of RPL group.

DIAGNOSTIC_TESTMicrobiota analysis

A cervical microbiota analysis will be performed in the RPL and control groups.

Locations(1)

Hospital de Clínicas de Porto Alegre (HCPA)

Porto Alegre, Rio Grande do Sul, Brazil

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NCT06604338

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