Selection of Resistant Mutations to Dolutegravir in PLWH Treated in Mozambique
Selection of Resistant Mutations to Dolutegravir and Associated Drugs in PLWH Treated in Clinical Practice in Chokwé, Mozambique
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
200 participants
Oct 25, 2024
OBSERVATIONAL
Conditions
Summary
The HIV infection not fully controlled, despite being under antiretroviral treatment, could make virus resistance against the antiretroviral treatments, making hardest the well control of HIV infection. The purpose of this research study is to confirm or deny if a not fully good controlled HIV infection could develop virus resistance against antiretroviral drugs that can difficult the good control of the HIV infection.
Eligibility
Inclusion Criteria4
- Patients able to understand and sign the informed consent form.
- Documented HIV-1 infection.
- Under the first line TLD for at least 6 months.
- At least 3 months follow-up with CV \>200c/ml.
Exclusion Criteria5
- Patients \<18 years of age.
- Under the first line regime other than TLD.
- Patients with active neoplastic processes.
- Patients with active opportunistic diseases.
- Patients unable to give informed consent.
Interventions
Not applicable- observational study
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06607588