RecruitingPhase 4NCT06607887

The Role of Postoperative Antibiotics in Laparoscopic Cholecystectomy


Sponsor

Minia University Hospital

Enrollment

300 participants

Start Date

Aug 30, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Comparison between postoperative parenteral prophylactic antibiotics, and oral antibiotics regarding the incidence of post laparoscopic cholecystectomy infection.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • Adult patients (aged above 18 years) undergoing laparoscopic cholecystectomy.

Exclusion Criteria1

  • patients with comorbidities (Diabetes, malignancies, Immunosuppressed). Lost of follow-up. Patients received antibiotics within 72 hr before admission. Complicated cases involved, gangrenous and perforated cholecystitis and abscess.

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Interventions

DRUGIV antibiotic

Parenteral prophylactic antibiotics (cefazolin), 1st dose at the time of induction of anesthesia, 2nd dose after 12hs from the surgery.

DRUGOral antibiotic

Parenteral prophylactic antibiotic (cefazolin), dose at the time of induction of anesthesia and then oral antibiotic for five days postoperative.


Locations(1)

Minia University Hospital

Minya, Egypt

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NCT06607887


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