RecruitingEarly Phase 1NCT06608134

Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Knee Osteoarthritis

Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for

Sponsor

R3 Medical Research

Enrollment

120 participants

Start Date

Oct 1, 2024

Study Type

INTERVENTIONAL

Conditions

Osteoarthritis, Knee

Summary

This is a Pilot Study which is randomized, prospective, open label, dose escalation, non-controlled evaluating safety and feasibility of intra-articular Wharton's Jelly (WJ) allograft will be evaluated in patients suffering with knee osteoarthritis. The participants will be randomized to one of three dosing treatment arms that will consist of one intra-articular knee injection containing either low dose, medium dose or high dose WJ allograft tissue.

Eligibility

Min Age: 30 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called Umbilical Cord Wharton's Jelly Allograft Intra-articular Knee Injection for people with osteoarthritis, knee. The study is currently recruiting participants at 5 locations. People eligible for this study include aged 30 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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