RecruitingPhase 3NCT06611891

Evaluation of Somatostatin Receptor Expression in PET 68Ga-DOTATOC in Patients Followed for Metastatic Breast Cancer


Sponsor

University Hospital, Grenoble

Enrollment

25 participants

Start Date

Jan 6, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

DOTABREAST: Evaluation of Somatostatin Receptor Expression in PET 68Ga-DOTATOC in Patients Followed for Metastatic Breast Cancer This is a prospective, monocentric, non-controlled, non-randomized, open-label, interventional study.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 99 Years

Plain Language Summary

Simplified for easier understanding

This study uses a special PET scan with a radioactive tracer (68Ga-DOTATOC) to see if certain receptors found on tumors — called somatostatin receptors — are present in people with metastatic breast cancer. If so, this could open the door to new targeted treatments. Participants will get both a standard FDG-PET scan and this newer scan for comparison. **You may be eligible if...** - You are over 18 years old - You have metastatic breast cancer (cancer that has spread beyond the breast) - Your primary tumor is ER-positive and HER2-negative (a common hormone-driven subtype) - You have already completed at least one systemic treatment for metastatic disease - You have visible liver and bone metastases on standard imaging **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have poor kidney function - You have already received certain targeted therapies called PRRT - You are unable to have PET/CT scans Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUG68Ga-DOTATOC

Slow direct intravenous injection


Locations(1)

CHU Grenoble Alpes

Grenoble, France

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NCT06611891


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