RecruitingNot ApplicableNCT06612372
Effects of 60-day-6° Head-down Bed Rest on Cartilage and Function of the Knee Joint
Sponsor
Peking University Third Hospital
Enrollment
26 participants
Start Date
Sep 10, 2023
Study Type
INTERVENTIONAL
Conditions
Summary
Objective: To investigate the effects of long-term simulated unloading in bed on articular cartilage quality based on functional magnetic resonance imaging (FMRI) and Knee joint function.
Eligibility
Sex: MALEMin Age: 25 YearsMax Age: 50 Years
Inclusion Criteria1
- (1) male; (2) age 25-50 years old; (3) height between 160-175 cm, weight ≥50kg, and BMI between 18.5-26 kg/m²; (4) good general health status.
Exclusion Criteria1
- (1) history of alcoholism; (2) smoking ≥5 cigarettes/day in the 3 months before the test; (3) drug dependence or use of medications affecting bone metabolism within 2 weeks before screening; (4) presence of metal implants, severe vertigo, or severe snoring.
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Interventions
BEHAVIORAL60-day-6° head-down bed rest
Throughout the bed rest period, subjects carried out all activities of daily living-eating, voiding, recreation, and testing
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06612372
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