The Effects of Oscillatory Positive Expiratory Pressure (OPEP) Therapy in Patients With COPD

This study tests whether oscillatory positive expiratory pressure (OPEP) therapy — a breathing technique using a small handheld device that creates vibrations to help clear mucus from the airways — can improve breathing and quality of life in people with COPD and chronic bronchitis. **You may be eligible if...** - You are 40 years old or older - You are a current or former smoker with at least a 10 pack-year smoking history - You have a confirmed diagnosis of COPD from a breathing test (spirometry) - You have chronic bronchitis, meaning you regularly cough up mucus or have a productive cough most days **You may NOT be eligible if...** - You have had a COPD flare-up (exacerbation) requiring hospitalization in the past 4 weeks - You have recently started or changed inhalers - You have other serious lung conditions such as active tuberculosis or severe asthma - You are already using OPEP therapy Talk to your doctor to see if this trial is right for you.