Green Tea and Quercetin in Combination With Docetaxel Chemotherapy in Castration-resistant Prostate Cancer Patients

This study tests whether combining two natural compounds — green tea extract and quercetin (found in many fruits and vegetables) — with standard docetaxel chemotherapy can improve outcomes for men with castration-resistant prostate cancer (cancer that has stopped responding to hormone therapy). Both compounds have shown potential anti-cancer properties in lab studies. **You may be eligible if...** - You are a man 18 years or older - You have been diagnosed with metastatic prostate cancer - Your cancer is castration-resistant (progressing despite hormone therapy) - You are scheduled to receive docetaxel chemotherapy **You may NOT be eligible if...** - You have severe liver problems (green tea extract can affect liver function) - You have had prior treatment with docetaxel - You have serious heart, kidney, or bleeding conditions - You are taking blood thinners or other medications that may interact Talk to your doctor to see if this trial is right for you.