RecruitingNot ApplicableNCT06617013

GERD in Children With Cystic Fibrosis

Characteristics of Gastroesophageal Reflux in Children With Cystic Fibrosis


Sponsor

Duke University

Enrollment

20 participants

Start Date

Oct 23, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to evaluate the prevalence of gastroesophageal reflux disease (GERD) symptoms in pediatric patients with cystic fibrosis using the Gastroesophageal Symptom Assessment Scale (GSAS) and the impact of stopping anti-GERD therapy on the GERD symptoms reported.


Eligibility

Min Age: 2 YearsMax Age: 18 Years

Inclusion Criteria2

  • Children 2-18 years of age with a confirmed CF diagnosis by either a positive sweat test or 2 disease causing CFTR mutations.
  • Signed consent

Exclusion Criteria3

  • Declining to participate in the study or sign consent
  • History of severe GERD per gastroenterology diagnosis and documentation
  • GSAS score \>80

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Interventions

OTHERDiscontinuation of GERD therapy

GERD therapy will be discontinued at time of enrollment.


Locations(1)

Duke University Hospital

Durham, North Carolina, United States

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NCT06617013


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