RecruitingPhase 2NCT06617481

PET Scan Study to Detect Prostate Cancer in Patients with Early PSA Recurrence

RhPSMA-7.3(18F)-PET Scan to Detect Prostate Cancer in Patients with Early PSA Recurrence


Sponsor

AdventHealth

Enrollment

30 participants

Start Date

Sep 20, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Flotufolastat F-18, sold under the brand name Posluma, is a radioactive diagnostic agent for use with positron emission tomography (PET) imaging for prostate cancer. The research is being done to study the capability of 18F-rhPSMA-7.3 (flotufolastat F-18) PET scan to detect prostate cancer when there are very low levels of Prostate-Specific Antigen (PSA) following previous radical prostatectomy surgery.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating the use of a specific type of PET scan — using a radiotracer called flotufolastat F-18 (which targets PSMA, a protein found on prostate cancer cells) — to detect recurrent prostate cancer at very low PSA levels after prostate removal surgery. The goal is to find cancer earlier, before it fully returns. **You may be eligible if...** - You previously had prostate cancer treated with radical prostatectomy (surgical prostate removal) with the intent to cure - Your PSA level is now elevated — at least 0.1 ng/mL but less than 0.5 ng/mL — suggesting possible cancer recurrence **You may NOT be eligible if...** - You are planning to receive a contrast dye or another PET radiotracer within 24 hours before the scan - You are currently receiving androgen deprivation therapy (hormone therapy) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUG18F-rhPSMA-7.3 (Posluma)

PET Scan using Posluma for detection of early recurrence of prostate cancer.


Locations(1)

AdventHealth

Orlando, Florida, United States

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NCT06617481


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