RecruitingNot ApplicableNCT06617871

Mechanical Alignment vs Kalipered Kinematic Alignment Total Knee Arthroplasty

A Prospective, Randomized, Single-blinded Clinical Trial Comparing Mechanical Alignment vs Kalipered Kinematic Alignment Total Knee Arthroplasty Using Medacta Spherika


Sponsor

Northwestern University

Enrollment

95 participants

Start Date

Aug 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Knee replacement surgery can be performed in one of two ways. Traditionally the goal was for the new joint to be in a neutral position with respect to the femur (thigh bone). This is called Mechanical Alignment (MA). The neutral position is different than the human knee's natural position, so MA often requires the surgeon to make additional cuts to the ligaments and other soft tissue around the knee. More recently surgeons have started to place the new joint in a position that more closely replicates the natural alignment of the human knee. This is called Kinemetic Alignment (KA). KA can be done without additional soft tissue dissection but the procedure requires a higher level of precision that can be difficult to achieve in every case. Some studies have found no difference in outcomes between MA and KA, whereas others have found KA to be superior. But these were small studies or studies that did not consider patient-rated outcomes.


Eligibility

Min Age: 21 YearsMax Age: 79 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Kinematic Alignment (KA) Interventions: and a procedure called Mechanical Alignment (MA) for people with knee osteoarthritis and knee arthropathy. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREMechanical Alignment (MA)

Primary TKA with the Medacta SpheriKA, utilizing either MA methodology.

PROCEDUREKinematic Alignment (KA) Interventions:

Primary TKA with the Medacta SpheriKA, utilizing either KA methodology.


Locations(1)

Northwestern Medicine

Chicago, Illinois, United States

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NCT06617871


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