The Effect of Mediterranean Diet and Mindfulness Eating on Depression Severity in People With Obesity and Major Depressive Disorder

This study is testing whether following a Mediterranean diet combined with mindful eating can improve depression in people who are both obese and depressed. Researchers are looking at whether these lifestyle changes can work alongside or even reduce the need for antidepressant medication. **You may be eligible if...** - You are 18 or older - You have been diagnosed with major depression and have at least moderate symptoms (BDI-II score of 20 or higher) - You have obesity (BMI of 30 or above) - Your antidepressant medication or therapy has not changed in the past 4 weeks - You currently eat a low-quality diet (low adherence to Mediterranean diet and mindful eating patterns) **You may NOT be eligible if...** - You have gut or digestive conditions that would prevent dietary changes (e.g., irritable bowel syndrome, post-bariatric surgery) - You have type 1 diabetes or chronic kidney disease - You have severe food allergies that prevent following the Mediterranean diet Talk to your doctor to see if this trial is right for you.