A Study on Pain After Breast Reconstruction
Persistent Postmastectomy Pain: Defining the Burden of Disease and the Role of Surgical Reinnervation in Patients With Breast Reconstruction
Memorial Sloan Kettering Cancer Center
500 participants
Oct 1, 2024
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to find out how common persistent postmastectomy pain (PPMP) is among people who have had a mastectomy and breast reconstruction surgery for their breast cancer. The study will also look at how effective regenerative peripheral nerve interface (RPNI) surgery is for reducing pain from neuropathic PPMP after breast reconstruction.
Eligibility
Inclusion Criteria6
- Female
- Age ≥18 years
- History of mastectomy for breast cancer or genetic predisposition to breast cancer
- History of breast reconstruction with implants and/or autologous tissue
- At least 6 months of follow-up after reconstruction
- Patient treated at MSK
Exclusion Criteria3
- Exchange or revision surgery within 6 months
- Active medical reason for pain (e.g., infectious, neoplastic, wound related)
- Greater than 15 years post-reconstruction
Interventions
PROMIS Scale v2.0 - Pain Intensity 3a is a 3-question short form in which patients rate their worst, average, and current level of pain during the past 7 days.
PROMIS 29+2 (PROMIS-Preference, PROPr) is a compilation of item banks to assess pain intensity
5-question short form that identifies patients who have experienced nociceptive pain during the past 7 days
5-question short form that identifies patients who have experienced neuropathic pain during the past 7 days
Locations(7)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06627582