RecruitingNCT06632431

Clinicopathological Analysis of Endometrial Carcinoma in the View of Old and New International Federation of Gynecology and Obestetrics (FIGO)

Sponsor

Assiut University

Enrollment

110 participants

Start Date

Oct 10, 2024

Study Type

OBSERVATIONAL

Conditions

Endometrial Carcinoma Clinicopathological Federation of Gynecology and Obestetrics

Summary

Assess the percentage change in stage and risk stratification for patients with endometrial cancer when transitioning from the FIGO 2009 endometrial staging system to the updated FIGO 2023 endometrial staging system. Investigate the prognostic impact of the FIGO 2023 endometrial staging system on patient survival. Evaluate how the shift in stage classification between the FIGO 2009 and FIGO 2023 systems influences adjuvant management decisions for endometrial cancer.

Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This is a records-based study reviewing medical files of patients who were treated for uterine (endometrial) cancer to better understand how different staging and classification systems compare. Researchers are looking back at cases from 2018 to 2022 to see how the old and new international cancer staging guidelines affect treatment decisions and outcomes. **You may be eligible if...** - You were diagnosed with endometrial (uterine) cancer - You had surgery (hysterectomy and removal of both ovaries and fallopian tubes) between January 2018 and December 2022 - Your medical records, tissue slides, and at least 2 years of follow-up data are available - You received follow-up treatment after surgery **You may NOT be eligible if...** - You received chemotherapy before surgery - You had a recurrence of endometrial cancer - You had multiple types of cancer at the same time - Your tissue samples or medical records are incomplete Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHEREndometrial cancer (EC)

Endometrial cancer (EC) who underwent surgical staging (total hysterectomy and bilateral salpingo-oophorectomy) Histopathological slides for these cases will be reexamined and staged according to both the Federation of Gynecology and Obestetrics (FIGO) 2009 and updated Federation of Gynecology and Obestetrics (FIGO) 2023 endometrial staging systems. Upstaging refers to reclassification to a higher stage in the FIGO 2023 system compared to Federation of Gynecology and Obestetrics (FIGO)2009, while downstaging is the opposite. All patients underwent lymph node dissection except those with Stage IA-Grades I and II endometrioid endometrial cancer and tumor size \<2 cm.