RecruitingNCT06633276

Fast and Accurate Breast Cancer Diagnosis Using Nanopore Sequencing in Tanzania (Fast-ABCD Sequencing)

Nanopore Sequencing for Accelerating Breast Cancer Diagnosis in Tanzania: A Prospective Observational Study


Sponsor

University of Bonn

Enrollment

100 participants

Start Date

May 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This pilot study will test the feasibility of using nanopore sequencing for breast cancer diagnosis in Tanzania. It aims to show that nanopore sequencing is non-inferior to the current standard of care, with the potential for faster and more cost-efficient results. By enhancing the speed and accuracy of diagnosis, this approach could improve treatment planning and outcomes for patients in resource-limited settings.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Patient with suspected diagnosis of breast cancer undergoing biopsy or surgical resection after specialist consultation as per institutional guidelines
  • Excess fresh tumor sample
  • Written informed consent

Exclusion Criteria2

  • Unable to provide informed consent
  • Patients who have already commenced therapy for BC (except for treatment other than biomedicine, e.g. herbal medicines)

Locations(1)

Kilimanjaro Christian Medical Centre

Moshi, Tanzania

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NCT06633276


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