RecruitingNot ApplicableNCT06634498

The Effect of Repetitive Transcranial Magnetic Stimulation for Internet Gaming Disorder

The Effect of Repetitive Transcranial Magnetic Stimulation of the Left Dorsolateral Prefrontal Cortex in Internet Gaming Disorder


Sponsor

Jin-tao Zhang

Enrollment

35 participants

Start Date

Oct 10, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to investigate the intervention effects of navigated repetitive transcranial magnetic stimulation (rTMS) on craving regulation in individuals with internet gaming disorder (IGD). The primary objectives include: (1) examining the impact of navigated rTMS over the dorsolateral prefrontal cortex (DLPFC) on the gaming cravings, and craving regulation capacity; and (2) exploring the potential neural mechanisms by which rTMS over the DLPFC improves craving intensity, and craving regulation ability.


Eligibility

Min Age: 18 YearsMax Age: 30 Years

Inclusion Criteria3

  • DSM-V gaming disorder \>5 and scored ≥ 50 on a revised version of Young's online Internet addiction test;
  • spent more than 50% of their online time gaming;
  • engagement in one of four popular Internet game (Arena of Valor,Genshine, LOL, FPS) for over 20 hours per week for at least 1 year.

Exclusion Criteria8

  • current or history of use of illegal substances and gambling;
  • current or history of psychiatric or neurological illness;
  • current use of psychotropic medications;
  • cognitive impairment as assessed by the Mini-International Neuropsychiatric Interview;
  • surgery, head trauma or heart related diseases in the past year;
  • a history of epilepsy or seizures or increased risk of seizures for any reason;
  • metal implants or tattoos of the neck or head;
  • claustrophobia.

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Interventions

OTHERreal rTMS on the dlPFC

During real rTM session, participants will perform the regulation of craving (ROC). In the rest phase, participants need to relax and rest. In the ROC task, participants will regulate craving elicited by gaming pictures using cognitive reappraisal. During the task, reaction times (RTs) and craving scores wil be recorded.

OTHERSham (No Treatment)

During the sham rTMS session, participants will perform the regulation of craving (ROC). In the ROC task, participants will regulate craving elicited by gaming pictures using cognitive reappraisal. During the task, reaction times (RTs) and craving scores wil be recorded.


Locations(2)

Medical Ethics Committee of Zhenjiang Mental Health Center

Zhenjiang, Jiangsu, China

State Key Laboratory of Cognitive Neuroscience and Learning

Beijing, China

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NCT06634498


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