RecruitingNot ApplicableNCT06638892

Using PrEP, Doing It for Ourselves

Cluster Randomized Controlled Trial of Using PrEP, Doing it for Ourselves [UPDOs] Protective Styles: A Multi-level Intervention to Improve HIV Testing and PrEP Uptake Among At-risk Populations Living in the Southeastern Region of the United States


Sponsor

Duke University

Enrollment

1,000 participants

Start Date

Feb 13, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to test a new online program called UPDOs Protective Styles to help people in the southeastern United States learn about and start using PrEP (pre-exposure prophylaxis), a medicine that helps prevent HIV. The study focuses on people who may be at higher risk for HIV and have not had equal access to PrEP. The main questions it aims to answer are: Does UPDOs help more people trust and understand PrEP? Does UPDOs increase the number of people who start and continue using PrEP? Researchers will compare two groups: One group will use UPDOs, which includes six weekly videos, blog discussions, and access to telehealth services through Q Care Plus. The other group will receive standard HIV prevention materials from the CDC. Participants will: Be recruited from 32 beauty salons in areas with high HIV rates. Complete surveys at the start of the study and again at 6, 12, 24, 32, and 52 weeks. Have access to HIV testing and PrEP prescriptions through Q Care Plus. This study will also look at how well the program works in different communities and how easy it is to use and share.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study (Using PrEP, Doing It for Ourselves) develops and tests a community-driven program to help Black cisgender women access and use PrEP — a daily medication that effectively prevents HIV infection. The program is designed by and for Black women to address their specific needs and barriers. **You may be eligible if...** - You identify as Black - You are a cisgender female (you were assigned female at birth and identify as a woman) - You are 18 years or older **You may NOT be eligible if...** - You are under 18 years old - You do not identify as Black - You are not a cisgender female Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALUsing PrEP, Doing it for Ourselves (UPDOs)

An e-Health intervention that considers women's lived experiences and uses three components: beauty salons and stylists as opinion leaders (trusted gatekeepers who share health information in the community), theory driven edutainment videos and blogs, and a secure online platform for accessing pre-exposure prophylaxis (PrEP).

OTHERStandard of Care

CDC standard of care, e.g., CDC videos and website.


Locations(1)

Duke University School of Nursing

Durham, North Carolina, United States

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NCT06638892


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