Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in Patients With Advanced Head and Neck Cancer

This trial is comparing two types of radiation for people with advanced head and neck cancer who are not suitable for curative treatment: stereotactic body radiotherapy (SBRT, a precise high-dose approach given in fewer sessions) vs. standard palliative radiation. **You may be eligible if...** - You are 18 years or older - You have confirmed squamous cell carcinoma of the head and neck (mouth, throat, larynx, or related areas) - Your doctor has determined that curative radiation is not an option for you - Your overall health allows you to receive radiation (ECOG 0-3) - You have had recent imaging of the head/neck and chest **You may NOT be eligible if...** - You have nasopharyngeal carcinoma - You have had prior chemotherapy or immunotherapy - You have had prior radiation to the head and neck - Your tumor is in certain high-risk locations (e.g., very large tumors, near the brain or optic nerves) - You have scleroderma or CREST syndrome - You have visible spread to distant organs Talk to your doctor to see if this trial is right for you.