Triple Assay of Rectal Mucus in the Diagnosis of Colorectal Cancer

This study is testing a new non-invasive method to detect colorectal cancer using a simple rectal mucus sample — the mucus lining of the lower bowel. Researchers will test three different markers in the mucus at the same time to see if this can help diagnose colon and rectal cancer more accurately and early. **You may be eligible if...** - You are 18 or older - You have been referred through an urgent suspected cancer pathway by your primary care doctor during the study period - You are willing to provide written consent **You may NOT be eligible if...** - You cannot undergo a digital rectal examination (DRE) - You have painful or complicated anal conditions (such as acute fissures, severe hemorrhoids, post-radiation changes, or an obstructing rectal tumor) that would make examination unsafe or uncomfortable Talk to your doctor to see if this trial is right for you.