RecruitingNCT06651047

PK/PD Analysis of Ceftazidime/Avibactam or Cefiderocol With or Without Fosfomycin for the Treatment of Difficult To-treat Gram-negative Infections

Pharmacokinetic/Pharmacodynamic Analysis of Ceftazidime/Avibactam or Cefiderocol With or Without Fosfomycin for the Treatment of Difficult To-treat Gram-negative Infections

Sponsor

University of Bologna

Enrollment

120 participants

Start Date

Jul 9, 2024

Study Type

OBSERVATIONAL

Conditions

Antimicrobial Resistance (AMR)Gram Negative Infection

Summary

A multicenter, national, prospective, observational pharmacological study of patients with difficult-to-treat Gram-negative infections treated with ceftazidime/avibactam (CAZ/AVI) or cefiderocol (CEF) monotherapy or combination therapy with ceftazidime/avibactam associated with fosfomycin (FOS) or cefiderocol associated with fosfomycin.

Eligibility

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with antimicrobial resistance (amr) and gram negative infection. The study is currently recruiting participants at 11 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(11)

Irccs Aoubo

Bologna, Italy

Azienda Ospedaliera di Rilievo Nazionale e di Alta Specializzazione (ARNAS) Garibaldi

Catania, Italy

ASST-FBF-Sacco

Milan, Italy

Azienda Ospedale - Università Padova

Padova, Italy

Istituto mediterraneo per i trapianti e terapie ad alta specializzazione (ISMETT)

Palermo, Italy

Policlinico Umberto I

Rome, Italy

Policlinico Universitario Campus Bio-Medico

Rome, Italy

Ospedale Pediatrico Bambin Gesù

Rome, Italy

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Rome, Italy

Azienda Ospedaliero Universitaria Senese

Siena, Italy

Città della salute e della Scienza, Molinette

Turin, Italy

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NCT06651047

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