RecruitingPhase 3NCT06653322
A Multi-centered,Randomized,Double-blind,Placebo-controlled Study to Evaluate the Efficacy and Safety of SHR-1703 in Eosinophilic Asthma
Sponsor
Guangdong Hengrui Pharmaceutical Co., Ltd
Enrollment
400 participants
Start Date
Nov 21, 2024
Study Type
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to evaluate the Pharmacodynamic, Efficacy and Safety of SHR-1703 in Asthma Patients with Eosinophil Phenotype
Eligibility
Min Age: 12 Years
Plain Language Summary
Simplified for easier understanding
This study is testing a new drug called SHR-1703 for people with eosinophilic asthma — a type of asthma driven by high levels of a white blood cell called eosinophils — that is not well controlled despite being on multiple inhaler medicines.
**You may be eligible if...**
- You are 12 or older and weigh at least 40 kg (about 88 lbs)
- You have had asthma for at least 1 year
- You are on medium or high-dose inhaled corticosteroids (ICS) plus at least one other controller medication
- Your blood eosinophil count is elevated (consistent with eosinophilic asthma)
- Your asthma is poorly controlled and you had at least one severe flare-up in the past year
- Your lung function testing (FEV1) shows reduced airflow
**You may NOT be eligible if...**
- Your asthma is well-controlled on current medications
- Your eosinophil count is not elevated
- You are pregnant or breastfeeding
- You have certain other serious lung or immune conditions
Talk to your doctor to see if this trial is right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
DRUGHR-1703
HR-1703 will be administered by SC injection.
DRUGPlacebo
Matching Placebo will be administered by the SC injection.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06653322