RecruitingNCT06653998

Feasibility and Safety of Early Mobilization and Rehabilitation in Intensive Care Unit Patients

Feasibility and Safety of Early Mobilization and Rehabilitation in Intensive Care Unit Patients. A Prospective, Multicenter Study

Sponsor

Claudia Aristizábal

Enrollment

220 participants

Start Date

May 10, 2024

Study Type

OBSERVATIONAL

Conditions

Intensive Care Unit Patients Intensive care Unit acquired weakness

Summary

Intensive Care Unit Acquired Weakness (ICU-AW) is a common complication of critical illnesses, occurring in approximately 50% of ICU patients and is strongly associated with increased morbidity, physical impairments, and both short- and long-term mortality. The main characteristics of ICU-AW are symmetrical generalised muscle weakness affecting both respiratory and limb muscles; however, the clinical phenotype may differ depending on age, disease burden, length of ICU stay, and mechanical ventilation duration. The objective of the present study is to evaluate the feasibility achieved and the safety outcomes reported in a cohort of critically ill patients who undergo early mobilisation and rehabilitation in intensive care units. This research is a multicentre prospective cohort study.

Eligibility

Min Age: 18 Years

Inclusion Criteria1

Patients ≥ 18 years of age admitted to the intensive care units.

Exclusion Criteria3

Patients requiring extracorporeal membrane oxygenation (ECMO).
Patients without indication for early mobilisation in the ICU (severe hemodynamic instability, acute brain or spinal injury with rest orders, anaemia (Hb \&amp;lt;8 mg/dl), thrombocytopenia (platelets \&amp;lt;50,000), active systemic inflammatory response according to institutional protocols).
Patients in the postoperative period of cardiac transplantation.

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Interventions

OTHEREarly mobilization and rehabilitation

In the initial assessment will be applied the ICU Mobility Scale, with the objective of establishing the patient\'s current level of function and determining the most appropriate type, intensity and duration of activity. The sessions, which will be conducted by a physiotherapist, will include therapeutic strategies such as bed exercises (both active and passive), electrical stimulation, use of an in-bed cycloergometer (for upper and lower limbs), sitting on the edge of the bed, bed transfers, bedside transfers from bed to chair, out-of-bed exercises, standing, and walking. The latter two activities are considered to be the most complex. Each session will last approximately 20 to 30 minutes and will be conducted once a day, on a daily basis throughout the patient\'s ICU stay. The last session wil be prior to discharge of the patient. During each session, the Borg Perception of Exertion Scale will be assessed in order to adjust the intensity of physical activity.