Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation Study

This study is testing whether a bedside device that continuously monitors IL-6 — a protein that spikes when the body is fighting a serious infection — can help doctors better track and manage sepsis (a life-threatening infection response) and septic shock in ICU patients. **You may be eligible if...** - You are 22 or older - You are an ICU patient who meets the clinical criteria for sepsis or septic shock (suspected or confirmed infection causing organ dysfunction, or requiring medications to maintain blood pressure) **You may NOT be eligible if...** - You are under 22 years old - You do not meet the diagnostic criteria for sepsis or septic shock - You are unable to provide consent (or a surrogate cannot) Talk to your doctor to see if this trial is right for you.