Correlation Between PLA Levels and Disease Severity in Patients With Sepsis Cardiac Insufficiency

This study is investigating whether measuring PLA (platelet-leukocyte aggregates — clusters of blood cells that form during inflammation and infection) in the blood can help predict how severe heart problems are in ICU patients with sepsis. **You may be eligible if...** - You are between 50 and 90 years old - You are hospitalized in the ICU with a diagnosis of both sepsis and cardiac insufficiency (heart dysfunction caused by the infection) - You are within 24 hours of your diagnosis - Your condition meets specific severity scoring criteria **You may NOT be eligible if...** - You are outside the 50–90 age range - You do not have both sepsis and cardiac involvement - You were diagnosed more than 24 hours ago Talk to your doctor to see if this trial is right for you.