RecruitingNCT06661252

Evaluation of Nasal Biomarkers for Objective Assessment of Disease Severity in Respiratory Disorders


Sponsor

Diag-Nose Medical Pty Ltd

Enrollment

250 participants

Start Date

Jan 8, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This research study is an observational, single site study quantifying expression of biomarkers of respiratory disease in nasal fluid using the ABEL microsampler device. The primary objective of this study is to compare biomarker expression between healthy controls and participants with respiratory disorders such as chronic obstructive pulmonary disorder (COPD), hayfever, chronic sinusitis, asthma and rhinitis.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study investigates whether nasal fluid samples — collected via a simple nasal swab — can be used to objectively measure how severe a person's respiratory condition is. It includes both healthy volunteers and people with rhinitis, sinusitis, asthma, or COPD. **You may be eligible if...** - You are 18 or older - You are either a healthy volunteer with no significant nasal or lung problems, OR you have a prior diagnosis of rhinitis, sinusitis, asthma, or COPD **You may NOT be eligible if...** - You are under 18 years old - You are currently pregnant - You have had nasal surgery or a nasal injury in the past 3 months - You have a nasal anatomical issue that would prevent safe sample collection - You have had an adverse reaction to a finger-prick blood test or nasal sampling Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEABEL microsampler device

The ABEL microsampler device will be used to collect nasal fluid samples for biomarker analysis.


Locations(1)

Diag-Nose Medical

Notting Hill, Victoria, Australia

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NCT06661252


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