RecruitingNCT06662045

Impact of Iron Deficiency Anemia on Neurobehavioral and Cognitive Development in Children Aged 6 to 24 Months

Study on the Association Between Iron Deficiency Anemia and Neurobehavioral Development and Cognitive Function in Children Aged 6 to 24 Months

Sponsor

Pingshan District Maternal & Child Healthcare Hospital of Shenzhen

Enrollment

1,000 participants

Start Date

Jan 1, 2024

Study Type

OBSERVATIONAL

Conditions

Iron-Deficiency Anemia Neurobehavioral Manifestations Growth Disorders Nutritional Status

Summary

The goal of this observational study is to explore the relationship between iron-deficiency anemia and neurobehavioral development in children aged 6-24 months. This study focuses on children who undergo health check-ups and blood tests at pediatric health clinics in Pingshan District, Shenzhen, China. The main questions it aims to answer are: How does iron-deficiency anemia affect children's neurobehavioral development, including motor skills, language ability, and social behavior? How does anemia influence growth and nutrition, such as weight, height, and body mass index (BMI) in children? Participants will: Undergo blood tests (including hemoglobin levels, serum ferritin, and serum iron) to assess anemia status. Be assessed using the "Neuropsychological Behavioral Development Scale for Children Aged 0-6" to measure motor, cognitive, language, and social development. Provide general health information, such as birth history, feeding methods, and parental details, through interviews with trained surveyors. Researchers will compare children with and without iron-deficiency anemia to determine differences in neurobehavioral outcomes and development levels. The findings aim to provide evidence for early interventions to prevent the negative impacts of anemia and support children's healthy development.

Eligibility

Min Age: 6 MonthsMax Age: 6 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at how iron deficiency anemia — a condition where the blood does not have enough healthy red blood cells due to low iron — may affect brain development, behavior, and thinking skills in babies and toddlers between 6 and 24 months old. **You may be eligible if...** - Your child is between 6 and 24 months old - Your child either has been diagnosed with iron deficiency anemia (for the study group) or has confirmed normal iron levels (for the comparison group) - You have lived in the study area for at least 6 months - You are willing and able to follow all study visits and procedures - Your child has completed all baseline evaluations **You may NOT be eligible if...** - Your child has a birth defect or long-term condition that could affect brain development, such as Down syndrome or cerebral palsy - Your child had a serious infection or injury in the past 3 months - Your child has recently received iron supplements or a blood transfusion (within the last 6 months) - Your child was born prematurely (before 37 weeks) or had a low birth weight (under 2,500 grams / about 5.5 lbs) - You are not able or willing to follow the study procedures Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.