RecruitingNot ApplicableNCT06662435

GYNecologic Cancer-Related COGnitive Impairment

A Pilot and Mixed-Methods Study of GYNecologic Cancer-Related COGnitive Impairment


Sponsor

Northwestern University

Enrollment

60 participants

Start Date

Feb 7, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to test a home-based and patient-tailored cognitive training intervention among gynecologic cancer patients who have completed chemotherapy and who have experienced cancer-related cognitive impairment.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at ways to help women who notice problems with thinking, memory, or concentration after completing chemotherapy for gynecologic cancers such as ovarian, uterine, cervical, or vulvar cancer. These thinking problems — sometimes called "chemo brain" — are common but often overlooked. **You may be eligible if...** - You are a woman aged 18 or older - You have been diagnosed with a gynecologic cancer and have finished chemotherapy, with your disease currently stable or in remission - You have noticed at least one problem with your thinking, memory, or concentration - You are fluent in English and have internet access to complete assessments **You may NOT be eligible if...** - You have not received chemotherapy as part of your cancer treatment - You have a pre-existing neurological or psychiatric condition that affects thinking (such as dementia, Alzheimer's, or schizophrenia) - You have a non-gynecologic cancer that is incurable and spreading - You are already participating in a cognitive training program or another cognitive trial - You have a self-reported learning disability or are unwilling to use technology-based brain training programs - You are pregnant or currently incarcerated - You are not able to make decisions for yourself regarding study participation Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALGYNCOG

Participants in the GYNCOG arm will be asked to participate in a home-based cognitive training program utilizing BrainHQ. Participants will be instructed to use the Brain HQ app for approximately 2.5 hours per week. Patients will be provided with a calendar to help keep track of daily BrainHQ use, including the number of exercises completed and the amount of time spent on the app per day. Patients will be asked to undergo the exercises that target the speed and accuracy of information processing. Examples of the exercises include: Double Decision: This exercise tests your ability to quickly identify and choose between two options. Eye for Detail: It challenges participants to spot small differences between two similar images. Participants will be asked to train approximately 30 minutes per BrainHQ session, 5 times per week (i.e., 2.5 hours per week) for 10 weeks, for a total of approximately 25 hours.


Locations(1)

Northwestern University

Chicago, Illinois, United States

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NCT06662435


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