Effect of TXA on Reducing Bruising After Filler Injection
Does TXA Reduce Bruising After Hyaluronic Acid Filler Injection? A Prospective Half Face Study
University of Wisconsin, Madison
40 participants
Dec 5, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to look at the effect tranexamic acid (TXA) may have on reducing bruising, swelling, and pain after facial filler injection. The main question it aims to answer is: * Does the addition of TXA to hyaluronic acid (HA) reduce bruising, swelling, and tenderness after HA injection? Participants will receive the study medication along with the standard facial filler injection and complete surveys.
Eligibility
Inclusion Criteria3
- Age equal to or greater than 18 but less than or equal to 89 years.
- Participants interested in facial filler (HA) injection.
- English speaking.
Exclusion Criteria13
- Minors or under the age of 18
- Participant over the age of 89
- Pregnant or breast-feeding women
- Individuals unable to give consent due to another condition such as impaired decision-making capacity.
- Individuals with a history of a thrombotic event (DVT, PE, stroke, MI) or genetic disorder that increases risk of thrombosis
- Participants undergoing unilateral facial filler (HA) injection
- Participants with history of hypersensitivity to TXA or any of the other ingredients
- Participants that are on current therapeutic anticoagulation therapy and aspirin use
- Participants with stage 2 or greater renal failure
- Participants on hemodialysis or peritoneal dialysis
- History of diabetes or seizures
- Current tobacco smokers
- Acquired defective color vision
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Interventions
Injectable gel
Injection of TXA
Injection of saline
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06665594