Effect of Force Magnitude on Canine Retraction and Gingival Crevicular Fluid Proteome
A Randomized Clinical Trial Comparing the Effect of Force Magnitude on the Rate of Canine Retraction and Gingival Crevicular Fluid Proteome Profile
UConn Health
40 participants
Nov 13, 2024
INTERVENTIONAL
Conditions
Summary
This study aims to examine the effect of force levels in orthodontic treatment during canine retraction. Force levels refer to the pressure applied by the orthodontic devices to move teeth. Data collection will include gingival fluid, dental molds from a digital scanner, and x-rays of the upper canine region on both sides of the mouth during treatment. The null hypothesis to be tested is that there is no significant difference in the rate of canine movement between the light force and the heavy force levels.
Eligibility
Inclusion Criteria7
- Healthy patient, non-smoker
- Age: 11 - 16 years of age, inclusive.
- A full complement of dentition (central incisor to 1st molar) in the four quadrants, except second molars
- Patients requiring at least upper bilaterally maxillary 1st premolar extraction as a treatment plan (Class I bimaxillary protrusion/ crowding or Class II maxillary dentoalveolar protrusion/ crowding)
- At least 5 mm of space left between canine and 2nd premolar to be closed at the time of canine retraction
- At least six months after the extraction of first premolars and in a 0.019 x 0.025-inch stainless steel archwire in the maxilla
- The ability to read and understand English and to provide informed consent
Exclusion Criteria11
- Patients under 11 years of age and over the age of 16.
- Non-extraction treatment plan
- Extraction of maxillary tooth other than first premolars bilaterally.
- Evidence of poor oral hygiene
- Evidence of previous root resorption
- Missing or impacted tooth in any of the quadrant except 3rd molars.
- Medical issues that affect tooth movement
- Inability to provide oral and written consent to participate.
- Patient on medications that may alter bone metabolisms like bisphosphonates, oral contraceptives, or PTH (parathyroid hormone)
- Chronic illness or syndromic patients.
- Pregnant women, prisoners, and decisional impaired
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Interventions
Patients' participation in the study (T0) will be started at the stage of canine retraction. At this appointment, 0.019 x 0.025-inch stainless steel archwire will be placed; power arms will be fabricated from 17x25-inch stainless steel on the maxillary first molars and canines. The height of the power arm will be matched with the center of resistance of both canines and molars based on the root length measured on the periapical radiographs. The archwire will be engaged in the canine bracket using stainless steel ligature wire. NiTi coil spring calibrated for force magnitude (150g) at oral temperature will be used to deliver the assigned force will be engaged from the first molars to the canine power arms
Patients' participation in the study (T0) will be started at the stage of canine retraction. At this appointment, 0.019 x 0.025-inch stainless steel archwire will be placed; power arms will be fabricated from 17x25-inch stainless steel on the maxillary first molars and canines. The height of the power arm will be matched with the center of resistance of both canines and molars based on the root length measured on the periapical radiographs. The archwire will be engaged in the canine bracket using stainless steel ligature wire. NiTi coil spring calibrated for force magnitude (400g) at oral temperature will be used to deliver the assigned force will be engaged from the first molars to the canine power arms
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06668194