RecruitingNCT06669520

Correlation of Blood Serum Renalase and Microcirculation Obstruction in Patients with Acute Myocardial Infarction After Primary Percutaneous Coronary Intervention

Sponsor

The Third Xiangya Hospital of Central South University

Enrollment

200 participants

Start Date

Aug 1, 2024

Study Type

OBSERVATIONAL

Conditions

Acute Myocardial Infarction

Summary

This research will explore the association between blood serum renalase and microcirculation obstruction in patients with acute myocardial infarction (AMI) after primary percutaneous coronary intervention (PCI). The investigators aim to identify potential risk factors for microcirculation obstruction in AMI patients after PPCI.

Eligibility

Min Age: 18 Years

Inclusion Criteria6

Age ≥ 18 years;
STEMI symptom onset time < 12 hours;
STEMI symptom onset time 12-48 hours with persistent ischemic symptoms, hemodynamic instability, or life-threatening ventricular arrhythmias;
High-risk NSTEMI;
Emergency PCI;
Voluntary informed consent.

Exclusion Criteria5

Non-obstructive acute myocardial infarction;
Severe chronic kidney disease (defined as estimated glomerular filtration rate < 20 mL/min per 1.73 m²);
Life expectancy < 1 year;
Pregnant or planning to become pregnant;
Emergency PCI failure.

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Locations(1)

The Third Xiangya Hospital of Central South University

Changsha, Hunan, China

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NCT06669520

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