RecruitingNCT06670261

Diagnosis of Respiratory Disorders by the Numerical Modeling.

JUNE Project: Does the Modeling of Nasal Airflows Improve the Pathophysiological Understanding and the Diagnosis of Functional Respiratory Disorders?


Sponsor

University Hospital, Bordeaux

Enrollment

300 participants

Start Date

Jul 9, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Chronic Nasal obstruction (CNO) is not currently measurable objectively because clinicians use validated declarative self-questionnaires whose results are linked to the level of understanding, the acute or chronic clinical situation, fatigue, psychological state and the desired gain. Using numerical simulations of the passage of air in the nasal cavities determining specific airflow parameters, the respiratory comfort of healthy subjects and the CNO of patients treated for this pathology could be explained.


Eligibility

Min Age: 18 YearsMax Age: 69 Years

Plain Language Summary

Simplified for easier understanding

This observational study uses computational fluid dynamics (computer simulations of airflow) to objectively measure chronic nasal obstruction (CNO) — a condition affecting 20–25% of the population that currently has no reliable, reproducible measurement tool. Researchers analyze existing CT scan data from healthy individuals and patients with structural nasal problems (like a deviated septum) to see whether specific airflow patterns in the nasal cavity can explain the experience of nasal obstruction. Adults aged 18–70 with a BMI under 30 and either no nasal symptoms or a confirmed structural nasal obstruction requiring surgery are eligible; patients with inflammatory nasal conditions, prior nasal surgery, or uncontrolled lung disease are excluded. There is no patient follow-up in this study — it uses existing clinical and imaging records. This summary was prepared as patient-facing educational content using AI assistance.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERData collection

Retrospective pseudo-anonymized clinical and scannographic data from the routine management of patients in rhino-sinusology consultations.


Locations(1)

CHU de Bordeaux

Bordeaux, France

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06670261


Related Trials