RecruitingNCT06670677

Evaluation of the Clinical Benefit of the Aktiia Blood Pressure Monitoring for Early Awareness of Hypertension and Prediction of Cardiovascular Risk

OBPM_FORESEE2024: Evaluation of the Clinical Benefit of the Aktiia Blood Pressure Monitoring for Early Awareness of Hypertension and Prediction of Cardiovascular Risk in a Multi-ethnic European Population: an Observational Cohorts' Study


Sponsor

Aktiia SA

Enrollment

15,000 participants

Start Date

May 12, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Because Aktiia S.A. has been the first-ever company to put in the market an Optical Blood Pressure Monitoring device, there is a need for Aktiia S.A. to correlate for the first time continual Blood Pressure monitoring and the evolution of environmental and health factors to improve hypertension management.


Eligibility

Min Age: 21 YearsMax Age: 85 Years

Inclusion Criteria5

  • Adult subjects aged 21 to 85 years old
  • Subjects living in Switzerland, Germany or in the UK
  • Subjects that are:
  • Aktiia users owning a smartphone with either iOS or Android operating system (ARMs 1 and 2); or Aktiia non-users owning a smartphone with iOS or Android operating system (ARM 3)
  • Subjects agreeing to follow the study procedures.

Exclusion Criteria7

  • Subjects suffering from sustained cardiac arrhythmias that can lead to weak or unstable pressure pulses including resting tachycardia (heart rate at rest \> 120bpm) and atrial fibrillation;
  • Subjects suffering from pathologies that systematically reduce peripheral perfusion including Raynaud's disease, diabetes, renal dysfunctions (eGFR \< 30mL / min / 1.73 m2), untreated hyper-/ hypothyroidism, pheochromocytoma, or arteriovenous fistula;
  • Subjects suffering from polyneuropathy;
  • on pregnant women;
  • Subjects with damaged / injured skin at the wrists (for bracelet measurements) or at index fingers (for camera measurements)
  • Subjects with amputated index fingers (for camera measurements) or amputated upper limb;
  • Subjects below 21 years old and above 85 years old.

Interventions

OTHERLifestyle survey completion

For the next 10 years, starting at their inclusion in the research project and every 6 months thereafter: fill in an online survey on their lifestyle- health- socioeconomic environment. The completion of a survey lasts 5min maximum.

OTHERUnlimited on-demand blood pressure measurements with G2C

For the next 10 years: take unlimited on-demand measurements with the Aktiia G2C feature (finger measurement) while seated

OTHERContinual blood pressure measurements with G1

For the next 10 years: wear their 24/7 Aktiia G1 device continuously as they would outside the context of the research project.


Locations(2)

Fully remote study- no physical investigational site

Lausanne, Switzerland

Fully remote study- no physical investigational site

London, United Kingdom

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NCT06670677


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