RecruitingNot ApplicableNCT06670833

Novel Tools to Improve Management of Paediatric Community-Acquired Pneumonia - ToolCAP

ToolCAP: Novel Tools to Improve Management of Paediatric Community-Acquired Pneumonia


Sponsor

University of Bern

Enrollment

3,500 participants

Start Date

Apr 4, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The ToolCAP study aims to see if using ultrasound to look at the lungs when children have symptoms of a lung infection will safely allow doctors to improve how they treat those infections. The study will also look at if it's possible to improve how doctors decide which children need antibiotics. * Lung infections are the most common reason for children to go to the clinic/hospital. * Doctors usually give an antibiotic to every child with a lung infection. * Lung infections can be caused by 2 different types of germs - bacteria or viruses. * Antibiotics only work against bacteria and not against viruses. Lung infections caused by viruses don't need antibiotics as the body fights them by itself. * Lots of research now shows that only 1 in 4 children with a lung infection actually needs an antibiotic, as the rest only have a viral infection causing the symptoms. * This means that 3 in 4 children get an antibiotic when they don't need it. * Taking too many antibiotics can cause problems for children as it can cause diseases like diabetes or asthma. * Nowadays, due to too many people using too many antibiotics, experts are starting to worry that bacteria are starting to become resistant (stronger than the antibiotic). * Ultrasound of the lungs appears to be a way of safely looking at the lungs to see if there is an infection and may help doctors better decide who needs an antibiotic. This study includes children aged 2 months-12 years who come to the hospital with a lung infection. Children who are very unwell or who have already had 2 days of antibiotic treatment will not be allowed to be in the study.


Eligibility

Min Age: 60 DaysMax Age: 12 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Lung ultrasound and Standard of Care (SOC) for people with imci guidelines, lrti, and other related conditions. The study is currently recruiting participants at 9 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERLung ultrasound

Portable lung ultrasound

OTHERStandard of Care (SOC)

SOC antibiotic treatment


Locations(9)

Université Cheikh Anta Diop

Dakar, Senegal

Centre National Hospitalier d'Enfants Albert Royer

Dakar, Senegal

Centre De Santé Gaspard Kamara

Dakar, Senegal

Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University

Parow, Cape Town, South Africa

University of Witwatersrand, MRC/Wits Rural Public Health and Health Transitions Research Unit

Parktown, Johannesburg, South Africa

Tintswalo Hospital

Acornhoek, Mpumalanga, South Africa

Themba Hospital

Mbombela, South Africa

Ifakara Health Institute

Ifakara, Morogoro, Tanzania

Muhimbili University of Health and Allied Sciences

Dar es Salaam, Tanzania

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NCT06670833


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