Magnetic Seizure Therapy for Schizophrenia - Trial

This study is testing Magnetic Seizure Therapy (MST) as a treatment for schizophrenia that has not responded well to antipsychotic medications. MST uses a focused magnetic field to induce a brief, controlled brain seizure under anesthesia, similar to electroconvulsive therapy (ECT) but with fewer side effects. **You may be eligible if...** - You are 18 or older with a diagnosis of schizophrenia or schizoaffective disorder for at least 2 years - You have tried at least 2 antipsychotic medications at adequate doses for at least 6 weeks each, without sufficient improvement - Your symptoms are at least moderately severe based on a standard rating scale - You are currently an inpatient or outpatient and can give informed consent **You may NOT be eligible if...** - You have a metal implant in your brain or body that is incompatible with magnetic therapy - You have a seizure disorder or other neurological conditions that make this procedure unsafe - You are pregnant - You have significant heart conditions that increase anesthesia risk Talk to your doctor to see if this trial is right for you.