Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial

This study (called ICEMAN) is comparing two surgical approaches for people with early-stage invasive skin melanoma: a standard wide excision (removing a larger margin of skin around the tumor) versus a narrower excision (removing less surrounding skin). The goal is to find out whether taking a smaller margin is just as safe. **You may be eligible if...** - You are 18 or older with confirmed primary invasive skin melanoma - Your melanoma is clinical stage IA (with high-risk features) or stage IB according to current staging guidelines - Your melanoma's Breslow thickness is greater than 0.5 mm **You may NOT be eligible if...** - Your melanoma has spread to the lymph nodes or other organs - You have a rare type of melanoma (such as desmoplastic or uveal melanoma) that has different surgical guidelines - You are unable or unwilling to give informed consent Talk to your doctor to see if this trial is right for you.