RecruitingPhase 2NCT06680089

CD70-targeted immunoPET Imaging of Kidney Cancer

A Study of the Clinical Application of [18F]RCCB6 PET/ CT Imaging in the Diagnosis of Kidney Cancer


Sponsor

RenJi Hospital

Enrollment

300 participants

Start Date

Nov 27, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this study is to establish and optimize the \[18F\]RCCB6 PET/CT imaging method, and its physiological and pathological distribution characteristics, on the basis of which the diagnostic efficacy of the above imaging agent in renal cancer (especially clear cell renal cell carcinoma) wil be evaluated.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study tests a new type of PET scan (a full-body imaging scan) that uses a specially designed tracer targeting a protein called CD70, which is found on kidney cancer cells. The goal is to improve how kidney cancer is detected and staged. **You may be eligible if...** - You are between 18 and 80 years old - You have been diagnosed with kidney cancer (especially clear cell or papillary types) confirmed by biopsy, or you have a suspicious mass on imaging that may be kidney cancer - You are able to give informed consent **You may NOT be eligible if...** - You are pregnant - You have severe liver or kidney disease - You have had major surgery in the past month - You have a known allergy to antibody-based radiopharmaceuticals (the imaging agent used in PET scans) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUG[18F]RCCB6

Enrolled patients will receive 0.05-0.1mCi/kg of \[18F\]RCCB6. ImmunoPET/CT imaging will be acquired 1 hour after \[18F\]RCCB6 injection.


Locations(1)

Renji Hospital, School of Medicine, Shanghai Jiao Tong University

Shanghai, Shanghai Municipality, China

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NCT06680089


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