RecruitingPhase 2NCT06680089
CD70-targeted immunoPET Imaging of Kidney Cancer
A Study of the Clinical Application of [18F]RCCB6 PET/ CT Imaging in the Diagnosis of Kidney Cancer
Sponsor
RenJi Hospital
Enrollment
300 participants
Start Date
Nov 27, 2024
Study Type
INTERVENTIONAL
Conditions
Summary
The aim of this study is to establish and optimize the \[18F\]RCCB6 PET/CT imaging method, and its physiological and pathological distribution characteristics, on the basis of which the diagnostic efficacy of the above imaging agent in renal cancer (especially clear cell renal cell carcinoma) wil be evaluated.
Eligibility
Min Age: 18 YearsMax Age: 80 Years
Inclusion Criteria3
- Aged 18-80 year-old and of either sex；
- Histologically confirmed diagnosis of kidney cancer (especially clear cell renal cell carcinoma and papillary renal cell carcinoma) or suspected kidney cancer by diagnostic imaging;
- Capable of giving signed informed consent, including compliance with the requirements and restrictions listed in the informed consent form (ICF) and this protocol.
Exclusion Criteria4
- Pregnancy；
- Severe hepatic and renal insufficiency;
- History of serious surgery in the last month;
- Allergic to antibody or single-domain antibody radiopharmaceuticals.
Interventions
DRUG[18F]RCCB6
Enrolled patients will receive 0.05-0.1mCi/kg of \[18F\]RCCB6. ImmunoPET/CT imaging will be acquired 1 hour after \[18F\]RCCB6 injection.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06680089
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