Cognitive Recovery After Post Stroke Delirium (RECOVER)
Cognitive Recovery After Post Stroke Delirium [RECOVER] a Longitudinal Pilot Proof of Concept Study in Stroke Patients With/without Delirium
University Hospital Tuebingen
40 participants
Dec 1, 2023
INTERVENTIONAL
Conditions
Summary
RECOVER is a Proof-of-Concept study on cognitive functioning following a longitudinal design with three measurements (during the acute- and post-acute phases of a stroke and a 3-month follow-up) and two equally-sized stroke patient groups: a post-stroke delirium(PSD), and a non-PSD group (control group). Cognitive functioning will be assessed using a multi-component neuropsychological assessment and tasked-based functional MRI (introducing a modified working memory task).
Eligibility
Inclusion Criteria4
- Age ≥ 60 years
- Ischemic stroke: Stroke Onset ≤ 96h, hospital admission ≤ 48h
- NIHSS ≥ 1
- Informed consent by patient or legal guardian
Exclusion Criteria5
- Aphasia
- Pre-existing conditions such as Dementia, psychiatric disorders (e.g., Depression, Schizophrenia)
- MRI contraindication such as certain metal implants
- Reduced consciousness, defined as Glasgow Coma Scale (GCS) ≤ 8
- Delirium onset before study enrollment
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Multi-component cognitive assessment including following domains: attention \& information speed, executive functioning, verbal memory, language, visuospatial-construction and orientation.
Structural MRI (e.g., MPRAGE, DTI) and functional MRI (introducing a modified working memory task for stroke patients)
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06680336