A Study of NP-201 Acetate Injection in Healthy Adult Volunteers and in Patients With Mild-To-Moderate Active Ulcerative Colitis

This study tests the safety and appropriate dose of a new drug (NP-201 acetate) in two groups: healthy adults and people with mild-to-moderate active ulcerative colitis (an inflammatory bowel disease that causes sores in the large intestine). **You may be eligible if...** - You are between 18 and 60 years old - You are in generally good health (for the healthy volunteer portion) - Your BMI is between 18 and 32, and you weigh at least 50 kg - You have mild-to-moderate active ulcerative colitis (for the patient portion) - You are willing to use effective contraception throughout the study and for 90 days after **You may NOT be eligible if...** - You have significant heart, liver, kidney, or other major medical conditions - You are pregnant, breastfeeding, or planning pregnancy - You have recently used other experimental drugs Talk to your doctor to see if this trial is right for you.