Pharmaco-proteomic Platform to Evaluate Drug Interactions in Liver Transplant Patients
Development of a Pharmaco-proteomic Platform to Evaluate Potential Drug Interactions and Their Clinical Impact in Liver Transplant Patients Undergoing Multidrug Treatment
Pontificia Universidad Catolica de Chile
48 participants
Jun 1, 2023
OBSERVATIONAL
Conditions
Summary
The goal of this observational study is to enhance the ability to forecast kidney failure in liver transplant patients in the ICU under multidrug treatment by developing a computer platform that integrates mathematical models of drug interactions, proteomics, and clinical data. The main outcomes it aims to develop are: 1. Design the multidrug web computing platform with available information on drug pair interactions (DDIs). 2. Integrate the proteomic and clinical data of liver transplant patients into the IT platform. 3. Implement the multidrug web platform to predict the clinical evolution of liver transplant patients.
Eligibility
Inclusion Criteria1
- Liver transplant patients undergoing surgery at UC Christus Hospital
Exclusion Criteria2
- Patients on renal replacement therapy
- Patients for whom no clinical or pharmacological registry is available
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
The clinical impact associated with the use of multiple drugs in liver transplant patients during their stay in ICU will be evaluated.
Locations(3)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06682325