RecruitingNCT06682832

Comparison of Clinical Status of Individuals With COPD and Preserved Ratio Impaired Spirometry

Comparison of Exercise Capacity, Muscle Strength and Oxygenation, Arterial Stiffness, Physical Activity and Quality of Life in Individuals With Chronic Obstructive Pulmonary Disease and Impaired Spirometry With Preserved Ratio

Sponsor

Hacettepe University

Enrollment

54 participants

Start Date

Sep 18, 2025

Study Type

OBSERVATIONAL

Conditions

Chronic Obstructive Pulmonary Disease (COPD)Preserved Ratio Impaired Spirometry (PRISM)

Summary

Despite the globally varying high prevalence rate of the PRISm phenotype, there are no guidelines for its diagnostic evaluation and management. Further studies are needed on appropriate approaches for individuals with PRISm to improve respiratory symptoms and prognosis. As research continues to evolve, PRISm needs to be recognized as a critical component of pulmonary assessments and at-risk individuals need to be provided with appropriate treatment and follow-up to prevent progression to COPD. There are no studies in the literature comparing PRISm, respiratory muscle strength, peripheral muscle strength and oxygenation, arterial stiffness, physical activity level and sleep level in COPD and healthy individuals. The aim of this study was to compare respiratory muscle strength, peripheral muscle strength and oxygenation, arterial stiffness, physical activity level and sleep level in PRISm, COPD and healthy subjects.

Eligibility

Min Age: 40 Years

Inclusion Criteria13

Being \>40 years old,
Being diagnosed with PRISm,
Volunteering to participate in the study,
Not having any orthopaedic or neurological problems that may prevent participation in the measurements,
Co-operation with measurements
Being \>40 years old,
Being diagnosed with COPD,
To be clinically stable,
Volunteering to participate in the study.
Being \>40 years old,
Volunteering to participate in the study,
No known chronic health problems,
To be able to co-operate with the measurements.