A Phase II Clinical Trial of Artificial Intelligence-assisted One-stop Radiotherapy for Breast Cancer After Breast-conserving Surgery

This study tests whether using artificial intelligence (AI) to plan and deliver radiation therapy in a single streamlined session ("one-stop" radiotherapy) is safe and effective for women with breast cancer who have had breast-conserving surgery. **You may be eligible if...** - You are a woman aged 18–70 - You have newly diagnosed invasive breast cancer and had breast-conserving (lumpectomy) surgery with removal of lymph nodes - Your lymph nodes tested positive for cancer, but your surgical margins are clear - Your cancer has not spread to distant organs - Your heart function is adequate (ejection fraction ≥ 50%) - You have completed any required chemotherapy **You may NOT be eligible if...** - You have bilateral (both sides) breast cancer - You had only a sentinel lymph node biopsy without full lymph node removal - You had breast reconstruction or implants at the same time as surgery - You had a heart attack or unstable heart problems in the past 3 months - You have had prior radiation to the chest or another current cancer Talk to your doctor to see if this trial is right for you.