RecruitingPhase 1NCT06686914

The Effects of Cannabidiol on the Driving Performance of Healthy Adults by Dose and Sex

Sponsor

West Virginia University

Enrollment

300 participants

Start Date

Jun 30, 2025

Study Type

INTERVENTIONAL

Conditions

Cannabidiol Effects

Summary

The objectives/purpose of this study are to comprehensively investigate the effects of non-prescription CBD on driving performance, drowsiness, sedation, and cognitive function in a large sample of healthy adults aged 18-30 years, with additional characterization of effects by dose and by sex, using a rigorous RCT design which will naturally mitigate confounding factors.

Eligibility

Min Age: 18 YearsMax Age: 30 Years

Inclusion Criteria7

Possess a current drivers' license
Driven a motor vehicle at least once in the past 30 days
Able to read English
Test negative for all substances on a urine drug test and complete a test drive to ensure the absence of simulation sickness
Not taking any daily prescription medications (excluding birth control)
Not diagnosed with any serious chronic disease by a licensed healthcare provider (including but not limited to Alzheimer's and related dementias, Parkinson's disease or other neurodegenerative disorder, major depressive or anxiety disorder, schizophrenia or other serious mental illness, arrhythmias, cataracts, glaucoma, chronic obstructive pulmonary disease, diabetes, epilepsy, sleep apnea, and fibromyalgia)
Have an individual willing to drive them home after testing or be taken home by study staff after testing

Exclusion Criteria3

Currently smoke, vape or use tobacco products, used CBD in the past 30 days
Used illegal drugs in the past 30 days (e.g., cocaine/crack, heroin, methamphetamine, 3,4-methylenedioxy-methamphetamine, inhalants, phencyclidine, lysergic acid diethylamide, psilocybin mushrooms, or marijuana)
Are pregnant or lactating at time of study

Print for Your Doctor

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGCannabidiol (CBD) Oil 300mg

Cannabidiol (CBD) Oil 300mg, 1 dose

DRUGCannabidiol (CBD) Oil 150mg

Cannabidiol (CBD) Oil 150mg, 1 dose

DRUGPlacebo Oil

Placebo Oil, 1 dose

Locations(1)

West Virginia University

Morgantown, West Virginia, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06686914