RecruitingNCT06688500

Bowel Dysfunction and HoLEP Outcomes


Sponsor

Northwestern University

Enrollment

126 participants

Start Date

Oct 5, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The objective of this prospective study is to examine the correlation and effects of bowel dysfunction on outcomes for patients undergoing holmium laser enucleation of prostate (HoLEP) for lower urinary tract symptoms secondary to benign prostatic hyperplasia (BPH).The investigator hypothesizes that patients who have more bowel dysfunction based on higher severity scores on patient-reported validated questionnaires will experience more symptoms in the immediate post-operative period and may have slower recovery of urinary control. Assessment of pre, peri, and post-procedural bowel dysfunction via the Constipation Severity Score (CSS) and Vaizey Incontinence Questionnaire will aid the analysis.


Eligibility

Sex: MALEMin Age: 18 YearsMax Age: 89 Years

Inclusion Criteria3

  • Males18-89 undergoing HoLEP
  • Able to read, understand, and complete patient questionnaires
  • Willing to sign the informed consent form

Exclusion Criteria6

  • Patients with bowel diversion (colostomy, ileostomy)
  • Patients with known neurogenic bowel
  • Patients having concurrent ureteroscopy+/-laser lithotripsy, percutaneous nephrolithotomy, or non-urologic surgery at time of HoLEP
  • Anticipated need for perineal urethrostomy at time of HoLEP
  • Prior pelvic radiation or patients with history of bladder cancer with or without Bacillus Calmette-Guerin (BCG) therapy
  • Patients who lack decisional capacity

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Interventions

PROCEDUREBowel function post Holmium Laser Enucleation of the Prostate

Observing post operative bowel functions among participants who have undergone a HoLEP procedure.


Locations(1)

Northwestern Medicine

Chicago, Illinois, United States

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NCT06688500