Chlorhexidine Antiseptic Irrigation of the Bowel Segment During Radical Cystectomy and Urinary Diversion

This study is testing whether rinsing a portion of the bowel with chlorhexidine (a common antiseptic) during bladder removal surgery (radical cystectomy) reduces the risk of infection. When bladder cancer requires removing the bladder, surgeons use part of the bowel to create a new urinary tract — this antiseptic rinse may reduce bacteria-related complications afterward. **You may be eligible if...** - You are 18 or older - You have been diagnosed with bladder cancer - You are scheduled for radical cystectomy (bladder removal) with urinary diversion surgery - You have a good performance status (ECOG 0–2) and acceptable kidney function **You may NOT be eligible if...** - You have untreated or unstable medical conditions - Your kidney function is significantly impaired (creatinine above 1.5 mg/dL) - You are unable or unwilling to follow the post-operative irrigation instructions Talk to your doctor to see if this trial is right for you.