RecruitingNot ApplicableNCT06692062

Hypofractionated Radiotherapy for Thymic Epithelial Tumors

A Prospective Study of Hypofractionated Radiotherapy for Thymic Epithelial Tumors


Sponsor

Rongrong Zhou

Enrollment

100 participants

Start Date

Oct 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to learn if hypofractionated radiotherapy works to shorten the treatment time without increasing the side effects in patients of thymic epithelial tumors. The main questions it aims to answer are: * Does Hypofractionated radiotherapy provide better results? * Can hypofractionated radiotherapy reduce toxic and side effects compared with conventional radiotherapy? Researchers will compare the efficacy and safety of hypofractionated radiotherapy after thymic tumor surgery. Participants will: * Receive hypofractionated radiotherapy or conventional radiotherapy * Visit the hospital regularly once every 12 weeks for checkups and tests


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a shorter, more intense radiation treatment schedule (called hypofractionated radiotherapy) for people with thymic tumors — cancers that start in the thymus gland in the chest. Researchers want to know if this approach works as well as standard radiation while being more convenient for patients. **You may be eligible if...** - You are between 18 and 74 years old - You have been diagnosed with a thymoma (type A, AB, B1, B2, or B3) or thymic carcinoma, confirmed by a tissue biopsy - Your cancer is at an early to intermediate stage (stage I, II, or III) - You are in reasonably good health and able to carry out daily activities - Your doctor expects you to live at least one more year - You have adequate bone marrow and organ function **You may NOT be eligible if...** - You have already received radiation therapy to the chest - You have had a recent heart attack or have poorly controlled heart failure - You have an uncontrolled infection or serious mental illness - You have another cancer that is not under control - You have a known history of mental illness or substance abuse Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

RADIATIONHypofractionated Radiation Therapy

R0 resection: 45-50Gy/20-25f R1 resection: 54-56Gy/25-28f R2 resection: 60-70Gy/30-35f


Locations(1)

Xiangya Hospital, Central South University

Changsha, Hunan, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06692062


Related Trials