RecruitingNCT06692790

VEHICLE Registry: Venous Stenting for IIH in the MENA Region

Venous StEnt for Idiopathic IntraCranial HypertEnsion (VEHICLE) Registry: Management and Outcomes in the MENA Region


Sponsor

Middle East North Africa Stroke and Interventional Neurotherapies Organization

Enrollment

150 participants

Start Date

Aug 11, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

The VEHICLE Registry is a multicenter observational study aimed at evaluating the management and outcomes of patients with Idiopathic Intracranial Hypertension (IIH) undergoing venous sinus stenting in the Middle East and North Africa (MENA) region. The study focuses on assessing clinical characteristics, treatment efficacy, safety, and the role of venous sinus stenting as a therapeutic modality in IIH.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This registry is collecting data from patients in the Middle East and North Africa (MENA) region who undergo venous sinus stenting — a minimally invasive procedure to open a narrowed vein in the brain — as a treatment for idiopathic intracranial hypertension (IIH), a condition where pressure inside the skull is too high with no known cause. **You may be eligible if...** - You are between 18 and 60 years old - You have been diagnosed with IIH, which means you have symptoms like headaches and vision problems, high pressure on spinal fluid testing, and no other explanation for the pressure - Imaging shows a narrowing (stenosis) in your brain's venous drainage system - You have not responded to medications like acetazolamide, or cannot tolerate them - You are willing to undergo the venous stenting procedure **You may NOT be eligible if...** - Your elevated brain pressure has a known secondary cause (such as a tumor or blood clot in the brain veins) - You have a blood clotting disorder or cannot take blood thinners - You are pregnant or breastfeeding - You are unable to complete follow-up visits - You have serious other medical conditions that make the procedure unsafe Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERVenous Sinus Stenting Procedure

Performed under general or local anesthesia. Targeted stenosis sites included the right transverse sinus, left transverse sinus, bilateral transverse sinuses, and right transverse and sigmoid sinuses. Stents used included Venous Sinus Stent (CWS), CASPER, PRTCS, and multiple stents where necessary. Post-procedure care included antiplatelet therapy and routine follow-up assessments


Locations(2)

Alexandria University

Alexandria, Egypt

King Abdullah Medical City (KAMC) -

Mecca, Saudi Arabia

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NCT06692790


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