RecruitingNot ApplicableNCT06695793

Niche Investigated: Closure of Hysterotomy & Evaluation of 3 Suturing Techniques (Running, Interrupted, and Locked)


Sponsor

Cairo University

Enrollment

225 participants

Start Date

Nov 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to explore the impact of three different suturing techniques (Running, Interrupted \& Locked) that used to close the uterine incision at the cesarean section on the formation of a cesarean scar niche


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 35 Years

Inclusion Criteria5

  • Women with a singleton pregnancy scheduled for elective cesarean section
  • Gestational age at the time of cesarean section between 38 and 40 weeks.
  • Willingness to participate in the study and provide informed consent
  • Age between 18 and 35 years old.
  • BMI <30

Exclusion Criteria7

  • Known uterine anomalies or previous uterine surgery (e.g, myomectomy, uterine septum resection)
  • Pre-existing medical conditions contraindicating cesarean delivery or affecting uterine healing (e.g., Anemia, Diabetes)
  • Current smokers.
  • Non-cephalic presentation of the fetus.
  • Low-lying anterior wall placenta and placenta previa.
  • Inability to provide informed consent (e.g., cognitive impairment, language barrier)
  • Any condition deemed by the attending physician to pose a risk to the participant or compromise the study's integrity, for example, Patients who will require excessive suturing for further hemostasis or those who require ligation of one or both uterine arteries

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Interventions

PROCEDUREInterrupted Sutures

The first layer of uterine incision will be closed using individual, separate sutures placed at regular intervals along the incision line. Each suture will be tied independently, ensuring adequate apposition of uterine tissue, followed by a second layer of running continuous sutures.

PROCEDURELocked Sutures

The first layer of uterine incision will be closed using continuous sutures placed along the uterine incision, incorporating a locking technique at specified intervals to prevent unraveling. The knots will be securely tied to maintain tissue approximation, followed by a second layer of running continuous sutures.

BIOLOGICALRunning Continuous Sutures

Double layer closure of uterine incision using running continuous suture used to close the uterine incision without interruption, providing seamless tissue approximation throughout the incision length.


Locations(5)

Cairo University

Cairo, Egypt

Cairo University

Cairo, Egypt

Cairo University

Cairo, Egypt

Cairo University

Cairo, Egypt

Cairo University

Cairo, Egypt

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NCT06695793