RecruitingNot ApplicableNCT06697106

Can COX-2 Inhibitor Decrease Stricture Recurrence After Direct Vision Internal Urethrotomy?


Sponsor

New Valley University

Enrollment

82 participants

Start Date

Nov 20, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

To evaluate the efficacy and safety of nonsteroidal anti-inflammatory drugs (NSAIDs) in preventing urethral stricture recurrence after direct visual internal urethrotomy.


Eligibility

Sex: MALEMin Age: 18 Years

Inclusion Criteria3

  • Age ≥ 18 years
  • American Society of Anesthesiologists (ASA) score ≤3.
  • Urethral stricture length ≤ 1.5 cm

Exclusion Criteria2

  • Recurrent urethral stricture ≥ 2 times.
  • Pelvic fracture urethral distraction defect (PFUDD).

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Interventions

DRUGNonsteroidal anti-inflammatory drugs

Patients will undergo direct vision internal urethrotomy (DVIU) plus nonsteroidal anti-inflammatory drugs (NSAID) for 3 weeks.

DRUGPlacebo

Patients will undergo direct vision internal urethrotomy (DVIU) plus a placebo for 3 weeks.


Locations(1)

New Valley University

New Valley, New Valley Governorate, Egypt

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NCT06697106